Dapoxetine / Priligy Review

my dapoxetineDapoxetine, also known as Priligy, is the first oral medicine specifically created to treat premature ejaculation.

It’s not currently available in every country, though is rapidly being approved in more every year.

It’s important to note that it can’t permanently cure premature ejaculation – you would have to take it every time you have sex.

Dapoxetine is a member of the selective serotonin reuptake inhibitor (SSRI) family of drugs, which are typically used as anti-depressants.

The original idea was actually to create a new anti-depressant, but it never came to be. Instead, it was found to work in delaying orgasm.

Anti-depressants are often prescribed by doctors to help with premature ejaculation. They’re well known to be effective in delaying ejaculation. But this is the first time a drug of this kind has been manufactured purely for this purpose.

It comes in 2 different dose levels – a 30mg and 60mg version. You would usually start on 30mg and move up to 60mg if necessary.

What makes it special?

Anti-depressants have long been offered men to help with premature ejaculation. For example, Fluoxetine (Prozac), Citalopram, Sertaline, Paroxetine, Clomipramine and Fluvoxamine. But there are problems associated with using these.

The main problem being that you need to take them every day. This is to ensure that the ejaculation delay effect will work when you come to have sex at any point during the day.

But would you want to take an anti-depressant every day if you don’t suffer from depression?

You may end up facing some of the common side effects of anti-depressants. More worryingly though are the side-effects that can affect your sexual function: a reduction in sexual libido or increased risk of sexual dysfunction. Out of the frying pan and into the fire as they say.

Dapoxetine though is very fast acting in comparison to those anti-depressants. The body absorbs it quickly, so you can take it a couple of hours before you think you might have sex. The body also eliminates it quickly, reducing the risk of the longer-term side effects.

The benefit then is that it can be used as an on-demand treatment for premature ejaculation. You don’t have to constantly cover yourself by taking a pill every day. This is a key point if you don’t have sex very frequently.

My experience

close up photo of priligy 30 mg

Dapoxetine still isn’t easily available in the United Kingdom. I was able to get hold of it privately though. This proved quite expensive, working out at about £15 per pill.

I actually tried it before the behavioral training program that has since improved my premature ejaculation problem, so this review is written in retrospect.

At the time my personal lasting time was very short. Between 1 and 5 minutes was the normal time I could have sex for without needing to stop and wait to calm down.

I did find that the 30 mg dose of Dapoxetine I took improved my lasting time. Over the couple of weeks that I experimented with it, I found I was able to last between 2 and 8 minutes on average.

So it didn’t exactly turn me into a marathon man overnight, but it was still an improvement. And the good thing was that it worked every time, as long as I took the tablets on average 2 hours before.

So that’s the good news. The bad news is the headaches. Dapoxetine is known to cause some side effects in a small percentage of men, and it seemed I was one of those.

The first time I thought it was perhaps due to the anxiety of trying out a new drug. But in fact I experienced unpleasant headaches the first 3 or 4 times I took it. It did seem to improve after that, but didn’t disappear altogether.

So would I recommend taking them? I’m not a medical professional, so it’s perhaps best to talk it through with your own doctor if you want to try it. I do recommend doing two things though:

  • That you don’t buy it online if you live in a country where it isn’t licensed for use yet.
  • That you consider whether you need a powerful drug like this to treat your premature ejaculation.

Which countries have approved Dapoxetine?

Currently Dapoxetine has been approved and marketed in over 50 countries, including: Sweden, Finland, Austria, Portugal, Germany, Italy, Spain, Mexico, South Korea, New Zealand, Australia, France, Malaysia, Philippines, Argentina and Uruguay.

It’s not currently approved by the FDA (Food and Drug Administration) in the United States, and is still undergoing phase III clinical testing.

It’s available in the United Kingdom, but not on the National Health Service, and only on a limited basis through private routes.

More countries are approving Dapoxetine for use every year, and it’s thought by experts that many more countries will eventually approve it.

Should I buy it online?

dapoxetine pills in a packet

If this arrived in the post – would you be 100% certain it’s an authentic product?

It’s a personal choice to buy Priligy online or not. However, it’s a choice which comes with risks attached.

There are a number of online pharmacies selling authentic Priligy; there are also a worryingly large number of online companies selling counterfeit products.

Are you sure you can tell the difference between a trustworthy and a fake source just from their website? If you’re determined to buy it online, then here are some things to consider:

  • If the website looks bad, is very small or only selling Dapoxetine, then look elsewhere.
  • Do some background checks on the company name of the website.
  • Some counterfeit drugs are ineffective, so you may end up wasting your money.
  • Some counterfeit drugs are dangerous. They may contain harmful components such as lead paint or animal poison.

There’s an eye-opening article written by the Pharmacy Times outlining the many dangers of buying prescription drugs from online pharmacies.

To me as well, the risks of taking fake drugs outweighs the benefits. It’s likely that Dapoxetine will be approved in many more countries eventually, so you may have an opportunity to try it in the future when it arrives in your country.

What evidence is there that it works?

The main evidence for the effectiveness of Dapoxetine can be found in a large research review conducted by Dr Chris G McMahon in 2012. He reviewed 5 different major studies which involved over 6000 men in total.

Here’s a summary of the main findings:

For men who last an average of 0.9 minutes, a 30mg dose increased that to 3.1 minutes, and 60mg increased it to 3.6 minutes. Patients on a placebo increased to 1.9 minutes. You can see this in the table below:

The average lasting time during sex, before and after taking Dapoxetine

Before30mg Priligy60mg PriligyPlacebo
0.9 minutes3.1 minutes3.6 minutes1.9 minutes

So it appears that on average Dapoxetine does increase the lasting time by a couple of minutes, which was my experience also. But is 3 minutes enough to satisfy both you and your partner?

The study does mention the change in men’s belief about their control level. Before the percentage of men saying they thought it was ‘good’ or better was 0.9%. With 30mg Priligy this was 26.2%. With 60mg Priligy it was 30.2%. And with the placebo it was 11.2%.

This level of satisfaction is similar then to a report in the UK website, Netdoctor, which says:

Unfortunately, the trial results we’ve seen so far suggest that in reality only about 45 per cent of men reported that the drug gave them control that was fair, good or very good.

So it seems then that the evidence that it works is strong, but it still might not be good enough for many men.

Side effects and safety

Dr McMahon also reviewed how many of the 6000 men experienced problems with the drug. The table below shows the percentage of men that experienced the more common Dapoxetine side effects.

Percentage of men experiencing side effects

Side Effect30mg when needed60mg when neededPlacebo

You can see then that many men do experience side effects when taking Dapoxetine. In addition to these common side effects, there were also reports of a very small number of men experiencing Snyope:

It was concluded that dapoxetine is associated with vasovagal-mediated syncope (a temporary inability of the brain to control blood pressure and heart rate adequately causing syncope), but otherwise caused no other cardiovascular adverse events.

In concluding, Dr McMahon does state though that Dapoxetine is safe to use for the majority of men. You should be aware that it does come with warnings that you shouldn’t take it if you have certain health conditions. That’s why it’s so important to discuss taking it with a doctor first.


The way you decide to treat premature ejaculation will always be a personal choice. The frustration it causes understandably leads many men to be willing to try almost anything.

With so much hype about Dapoxetine it’s easy to get carried away and hope that this is finally the cure you’ve been waiting for. There’s no doubt that it can help many men to improve their premature ejaculation, but it’s far from ideal.

Even if it does work, my personal tests found that it may only extend your lasting time by a couple of minutes. Whilst this is certainly an improvement, in my experience there are other options which can do better than that.


The best alternative which works quickly is probably a delay spray or cream.

And if you’re interested in tackling the problem through behavioral techniques, have a look at my recommended premature ejaculation guides.

And for a broader overview of premature ejaculation, the background and treatment options, have a look at this page.


  • Hai Sir. Am now studying M.pharmacy. Now in project period. so take the drug name of Depoxetine. But i ask 1 doupt, that it is any possibility of Depoxetine to make in Microsphere or Nano-particles form? If there pls rply ans to me. Thanking you Sir.

    • Hi Selvakumar.M
      I’m afraid I have no idea about making dapoxetine! I know what it does, and how it works, but I can’t offer any advice on the manufacturing process.

  • Has anyone taken 90mg of Priligy? Just curios to see if results better. I usually ejaculate within 2 mins without medication. On 30mg I can go on for 4 mins and on 60mg for about 6-7 mins. Maybe 90mg would last me 10 mins?

    • Hi George
      I haven’t personally, and don’t think I’d want to either because of the risk of side effects being worse. I’d recommend sticking to the recommended doses unless your doctor says it’s safe to take more.

    • I find giving the drug more time to works increases its efficacy a LOT! I maintain a window of three hours before activity. if I have sex like one and a half hours after taking it then it add minutes. but after three hours full control.
      Also drop and antihistamine 10 to 20 min before the Depo and the side effects that happen are almost non existent, that was a big relief for me as they were nasty.

      • Hi Simon
        Thanks for sharing your experience! Those are both interesting ideas – I’ll have to try the anti-histamine tip next time I decide to try dapoxetine. Did you do any research to see if they are ok to take together?

  • Hi friends i have been using Viagra for almost ten years no issues.now i have started taking combination pill that is 50 MG sildanifil citrate +30 MG dapoextene the name is called KUTUB 30 manufactured by a reputed manufacturer in india.if this taken once absolutly no issues and results are excellant.even after 20 to 30 minutes of fore play i am able to last and there after inter course of easily 5 to 8 minutes.but side effects starts if this is taken consequtively for 2 days.like head ache,diaheria,and sleeping long.so i have been advised by doctors not to take daily gap of minimum 24 to 48 hours is required to avoid side effect i can buy in india and send to any one who wants it.ASH,India.

    • Hi Ashok
      Thanks for sharing this – I hadn’t heard of this combination drug before, so it’s interesting to hear your experience of it. Unfortunately, I don’t encourage readers to use the comments as a means for supplying each other with drugs. Thanks for offering to help others though!

  • Please be careful of buying depoxatene online. Numerous online pharmacies sell ED meds and depox combined; one offered pill is avanafil 200 mg. + 30 mg. depoxatene. The avanafil is dosed at something like 4 times the largest “real pharmaceutical” dose. One pharmacy even sells a blend of tadalafil (Cialis – long acting), sildenafil (Viagra – fast acting) and a non-standard 50 mg. dose of depoxatene… tread very carefully here. I would seriously recommend talking to a doctor before swallowing *any* pill. Oh, and BTW, wearing a condom is often as effective as using a delay spray or depox, sometimes even more effective. And cheaper.

  • Hi! I live in the United States could someone tell me where I could buy Dapoxetine and feel safe about it? Thanks

    • Hi T J
      I couldn’t tell you personally – perhaps other readers from the US have experience of getting hold of it there?

    • TJ – There is no legal source in the U.S. at this time, which means buying from an Indian or Chinese online pharmacy. I don’t know if it would be allowed for me to publish the name of the online pharmacy where I bought depoxatene, but I’m sure the moderator will delete the link if not allowed: http://www.canadianpharma.com/ I have ordered four times from them, fast delivery etc. but frankly about 35% of the different ED meds I bought were ineffective and a waste of money. The remaining 65% of the products I tried were equivalent to the name-brand drugs. I take Cialis 20 mg. for ED. My local pharmacy charges something like$60.00 per pill (not covered by my insurance, of course), while my price at the online pharmacy was about $2.00/pill. Some of their generic Cialis (tadalafil) is made by Sipla, an Indian pharmaceutical company which also provides nearly all the AIDS medications sent to Africa by the World Health Organization (WHO) and is certainly trustworthy.

      • Hi there
        Thanks for this info. I’ll let the link through as I do know of this online pharmacy also.

  • MitchRappIngress@gmail.com:
    I am very happy with Dapoxetine, when properly dosed. I am moderate ED and mild/moderate PE. Without a ton of oral it’s almost impossible for me to bring my wife off before me and she can’t stand when I stop to maintain, even though I would just finish if I didn’t stop.
    So yes, I dose for both but very little. Sorry if this is in the other article but I haven’t read it yet. It’s best to start very small. I have 100mg Viagra but I chop them and take between 10-25 mg depending on the intensity of the night (without it I’m conscientious and lately stay flaccid (however I’ve always been conscientious and insecure though a pervert at heart)). Similarly I have the Dapoxetine HCL pictured above but mine are 90mg vs 60. I have and would never taken a full or half dose! I take around 10 mg. I have been happy to out last my mate when I take the combination but be careful… once I took about 25-30 (guessing because I just use a knife to split) at the same time as the Viagra, 2hrs before sex this time, and the Dap kept me down, that night and the next morning! The feeling when it works properly is a slight insensitivity kinda mild numbness (hence don’t take too much and get totally numb) My recommended dose and schedule is: Viagra 1/2hr to 3hr before sex and save the Dapoxetine for 15min-30 min before and small dose. When taken right you don’t need it the next morning and it might even offer benefits the next night. I also have Cialis and it’s not as ‘raging’ as Viagra but good for on call duration: I take 25mg-50mg and it’s usually dependable for the night and next day but I just might not be as firm. I now purchase generics only but have noticed a slight difference between the latest generic Viagra and Viagra Brand. It is “fluffier”, not as solid and I can pinch a dose off a 100mg tablet whereas the Brand Viagra is hard like a Tylenol…
    Just my personal experience and I love it! Mitch

    • Hi Mitch
      Thanks for your detailed comment sharing your experience. It’s very helpful to hear from other guys who’ve tried the products I talk about, and I know other readers really appreciate it too. I have a couple of questions – if you take the viagra 3 hrs before sex, do you still find it works well? And with the dapoxetine, how much longer do you think it helps you last on average? And do you find the viagra or cialis help you last longer on their own at all, or do you need the dapoxetine?

  • Thanks for the useful review. I’m looking for some medication to try as those delay sprays didn’t really work well for me. Might give dapoxetine a try.

  • Thank you for posting this topic. It’s great to hear other people’s experiances. How long does Prillogy last? A few hours? 24 hours? I’m lucky enough to be with a woman who enjoys having sex every day. Is it ok to take daily? I’m not finding much information with respect to these questions. Thanks guys!

    • Hi T
      You’re welcome, glad it was useful. The time it lasts will depend on factors such as your metabolism, but it won’t last 24 hours. You would need to take it again the next day, which is fine to do.

    • Hi Ivan
      Sure, it’s all about practicing certain techniques to control your arousal levels and then control your ejaculation response. There are techniques like the start and stop method, edging, kegels and reverse kegels which accompany an awareness of how your body responds to sexual stimulation. There are various other theories and techniques as well, incorporating everything from breathing to mental focus to position choices. If you’d like to find out more, you might find my review of the ejaculation trainer helpful – this was the training program I personally used to overcome PE.

  • Hi Ethan can priligy be taken along with cialis?
    Furthermore can my GP prescribe it for me on the approval of my urologist and will it be available in U.K. Pharmacy using that prescription?
    Please enlighten!

    • Hi Mak
      There are mixed thoughts about this. Some say no, because they can both cause dizziness so together it could be worse. Some say it’s absolutely fine. The best thing is to ask your doctor. You might also find that Cialis on its own is enough to help you last longer, or be able to have sex sooner after the first time. So I would start just with that and see if it helps, and if not maybe try the other as well.Your GP should be able to help you get hold of it, assuming they approve it.

  • I would rather take priligy than delay sprays, the whole point of having sex is to enjoy it, if you’re desensitized what’s the point? It sounds like nan had good results with 30 mg, I also think that a couple of minutes to some one that lasts seconds is a 3-4x improvement.

    The average time for men who don’t suffer from PE is 5 minutes, porn has skewed what is normal, if someone who ejaculates immediately upon penetration can last 3 min on priligy that’s a huge improvement as it’s almost the average. This sounds like a good medication to take while doing behavioral therapy, many men use cialis and viagra while behavioral therapy for porn induced ED weaning off until rehabilitation.

  • Priligy works normally very well with me and has really enhanced my sexual experiences. A 30 mg pill works even two days after eaten. However, it should be treated with respect, as the effect can be very nasty if you take a dose too large for you, you are too tired or you have taken alcohol, even if you are not drunk. Once I tried 60 mg and it literally knocked me down. About one hour after taking the pill, I suddenly realised that I was having tunnel vision, I could not follow the conversation, my pulse went up, sweat started running out my face and when I tried to stand up, the floor slided under my feet and I found myself in the floor. I didn’t loose consciousness, recovered after a few minutes and sex turned out quite okay. But never again 60 mg! After that, I have had two bad experiences with 30 mg (and about 16 good ones), one when I was exhausted and had some wine and one when I had alcohol several times throughout the day. I did not feel drunk, but about an hour after taking Priligy, my pulse went up and I felt shaky, dizzy, with nausea, diarrhoea and sweat poured out. I recovered after some minutes. If I can, I prefer to eat the pill more than one hour before I am going to meet my date.

    • Hi Nan
      Thanks for sharing your experience of priligy. To be honest, after reading this, my reaction would be to advise you to stop taking it! Have you spoken to your doctor about this? I think if you’re having all those side effects, even on the lower dose, it’s not good at all.

    • Hi Tinna
      Thanks for your comment. I think delay sprays are considerably better – assuming they work for you. If they do work, they might help him last longer than priligy.

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