Dapoxetine, also known as Priligy, is the first oral medicine specifically created to treat premature ejaculation.
It’s not currently available in every country, though is rapidly being approved in more every year.
It’s important to note that it can’t permanently cure premature ejaculation – you would have to take it every time you have sex.
Dapoxetine is a member of the selective serotonin reuptake inhibitor (SSRI) family of drugs, which are typically used as anti-depressants.
The original idea was actually to create a new anti-depressant, but it never came to be. Instead, it was found to work in delaying orgasm.
Anti-depressants are often prescribed by doctors to help with premature ejaculation. They’re well known to be effective in delaying ejaculation. But this is the first time a drug of this kind has been manufactured purely for this purpose.
It comes in 2 different dose levels – a 30mg and 60mg version. You would usually start on 30mg and move up to 60mg if necessary.
What makes it special?
Anti-depressants have long been offered men to help with premature ejaculation. For example, Fluoxetine (Prozac), Citalopram, Sertaline, Paroxetine, Clomipramine and Fluvoxamine. But there are problems associated with using these.
The main problem being that you need to take them every day. This is to ensure that the ejaculation delay effect will work when you come to have sex at any point during the day.
But would you want to take an anti-depressant every day if you don’t suffer from depression?
You may end up facing some of the common side effects of anti-depressants. More worryingly though are the side-effects that can affect your sexual function: a reduction in sexual libido or increased risk of sexual dysfunction. Out of the frying pan and into the fire as they say.
Dapoxetine though is very fast acting in comparison to those anti-depressants. The body absorbs it quickly, so you can take it a couple of hours before you think you might have sex. The body also eliminates it quickly, reducing the risk of the longer-term side effects.
The benefit then is that it can be used as an on-demand treatment for premature ejaculation. You don’t have to constantly cover yourself by taking a pill every day. This is a key point if you don’t have sex very frequently.
Dapoxetine still isn’t easily available in the United Kingdom. I was able to get hold of it privately though. This proved quite expensive, working out at about £15 per pill.
I actually tried it before the behavioral training program that has since improved my premature ejaculation problem, so this review is written in retrospect.
At the time my personal lasting time was very short. Between 1 and 5 minutes was the normal time I could have sex for without needing to stop and wait to calm down.
I did find that the 30 mg dose of Dapoxetine I took improved my lasting time. Over the couple of weeks that I experimented with it, I found I was able to last between 2 and 8 minutes on average.
So it didn’t exactly turn me into a marathon man overnight, but it was still an improvement. And the good thing was that it worked every time, as long as I took the tablets on average 2 hours before.
So that’s the good news. The bad news is the headaches. Dapoxetine is known to cause some side effects in a small percentage of men, and it seemed I was one of those.
The first time I thought it was perhaps due to the anxiety of trying out a new drug. But in fact I experienced unpleasant headaches the first 3 or 4 times I took it. It did seem to improve after that, but didn’t disappear altogether.
So would I recommend taking them? I’m not a medical professional, so it’s perhaps best to talk it through with your own doctor if you want to try it. I do recommend doing two things though:
- That you don’t buy it online if you live in a country where it isn’t licensed for use yet.
- That you consider whether you need a powerful drug like this to treat your premature ejaculation.
Which countries have approved Dapoxetine?
Currently Dapoxetine has been approved and marketed in over 50 countries, including: Sweden, Finland, Austria, Portugal, Germany, Italy, Spain, Mexico, South Korea, New Zealand, Australia, France, Malaysia, Philippines, Argentina and Uruguay.
It’s not currently approved by the FDA (Food and Drug Administration) in the United States, and is still undergoing phase III clinical testing.
It’s available in the United Kingdom, but not on the National Health Service, and only on a limited basis through private routes.
More countries are approving Dapoxetine for use every year, and it’s thought by experts that many more countries will eventually approve it.
Should I buy it online?
It’s a personal choice to buy Priligy online or not. However, it’s a choice which comes with risks attached.
There are a number of online pharmacies selling authentic Priligy; there are also a worryingly large number of online companies selling counterfeit products.
Are you sure you can tell the difference between a trustworthy and a fake source just from their website? If you’re determined to buy it online, then here are some things to consider:
- If the website looks bad, is very small or only selling Dapoxetine, then look elsewhere.
- Do some background checks on the company name of the website.
- Some counterfeit drugs are ineffective, so you may end up wasting your money.
- Some counterfeit drugs are dangerous. They may contain harmful components such as lead paint or animal poison.
There’s an eye-opening article written by the Pharmacy Times outlining the many dangers of buying prescription drugs from online pharmacies.
To me as well, the risks of taking fake drugs outweighs the benefits. It’s likely that Dapoxetine will be approved in many more countries eventually, so you may have an opportunity to try it in the future when it arrives in your country.
What evidence is there that it works?
The main evidence for the effectiveness of Dapoxetine can be found in a large research review conducted by Dr Chris G McMahon in 2012. He reviewed 5 different major studies which involved over 6000 men in total.
Here’s a summary of the main findings:
For men who last an average of 0.9 minutes, a 30mg dose increased that to 3.1 minutes, and 60mg increased it to 3.6 minutes. Patients on a placebo increased to 1.9 minutes. You can see this in the table below:
The average lasting time during sex, before and after taking Dapoxetine
|Before||30mg Priligy||60mg Priligy||Placebo|
|0.9 minutes||3.1 minutes||3.6 minutes||1.9 minutes|
So it appears that on average Dapoxetine does increase the lasting time by a couple of minutes, which was my experience also. But is 3 minutes enough to satisfy both you and your partner?
The study does mention the change in men’s belief about their control level. Before the percentage of men saying they thought it was ‘good’ or better was 0.9%. With 30mg Priligy this was 26.2%. With 60mg Priligy it was 30.2%. And with the placebo it was 11.2%.
This level of satisfaction is similar then to a report in the UK website, Netdoctor, which says:
Unfortunately, the trial results we’ve seen so far suggest that in reality only about 45 per cent of men reported that the drug gave them control that was fair, good or very good.
Side effects and safety
Dr McMahon also reviewed how many of the 6000 men experienced problems with the drug. The table below shows the percentage of men that experienced the more common Dapoxetine side effects.
Percentage of men experiencing side effects
|Side Effect||30mg when needed||60mg when needed||Placebo|
You can see then that many men do experience side effects when taking Dapoxetine. In addition to these common side effects, there were also reports of a very small number of men experiencing Snyope:
It was concluded that dapoxetine is associated with vasovagal-mediated syncope (a temporary inability of the brain to control blood pressure and heart rate adequately causing syncope), but otherwise caused no other cardiovascular adverse events.
In concluding, Dr McMahon does state though that Dapoxetine is safe to use for the majority of men. You should be aware that it does come with warnings that you shouldn’t take it if you have certain health conditions. That’s why it’s so important to discuss taking it with a doctor first.
The way you decide to treat premature ejaculation will always be a personal choice. The frustration it causes understandably leads many men to be willing to try almost anything.
With so much hype about Dapoxetine it’s easy to get carried away and hope that this is finally the cure you’ve been waiting for. There’s no doubt that it can help many men to improve their premature ejaculation, but it’s far from ideal.
Even if it does work, my personal tests found that it may only extend your lasting time by a couple of minutes. Whilst this is certainly an improvement, in my experience there are other options which can do better than that.
The best alternative which works quickly is probably a delay spray or cream.
And if you’re interested in tackling the problem through behavioral techniques, have a look at my recommended premature ejaculation guides.
And for a broader overview of premature ejaculation, the background and treatment options, have a look at this page.