Tramadol For Premature Ejaculation: Effective But Risky

pile of yellow and green Tramadol capsulesThe search for the Holy Grail of a medical treatment for premature ejaculation sometimes leads to unexpected places.

So it’s no surprise that another drug, Tramadol, has been popping up in medical journals in recent years as a potential solution.

A bit like Dapoxetine, Tramadol wasn’t designed for this purpose though; it’s actually a synthetic opioid analgesic used for moderate to severe pain relief.

But individual guys and researchers have discovered that it can also help improve premature ejaculation. I’ll discuss and reference some of these research studies a bit later.

But first I’ll talk about my experience of Tramadol, as I’ve seen first hand both the good and bad side of it.

The pain, the pleasure and the near dependency

A few years ago I had major surgery, and was given a large supply of Tramadol to take home from hospital to manage the pain. What they didn’t realize, and I’d forgotten, was that I’d also been given a large amount by my own doctor. I ended up with more than 200 x 50 mg pills.

Around a month after the surgery I was able to have sex again. One day I felt some pain returning, so decided to take a 50 mg Tramadol pill (I’d been off them for about a week). I then discovered to my delight that I lasted roughly 3 or 4 times longer than I used to.

So I decided to test if it was the Tramadol by using them once or twice more, and then also without. It turns out it was definitely the Tramadol helping.

Sounds great so far, right?

The problem was though that I twice experienced an issue with dependency on the Tramadol developing. First, I was craving a top up every 6 hours for pain relief when taking them after surgery. It took a conscious effort to cut down and stop.

Second, I was loving the fact that my sex life was much better with my accidental discovery later on. I remember thinking to myself that this was great, and I should get some more so I could take them every time I had sex.

Not so great after all then!

Luckily for me I was strong-minded enough to cut down after the surgery. And I also knew that taking them long-term for sex wasn’t yet proved to be safe. I was also getting some side effects like dizziness and just feeling weird (for want of a better description) when taking them.

Of course, this was just my experience Nonetheless it does seem to highlight three key points that researchers make:

  • That Tramadol can help with premature ejaculation.
  • That it can cause side effects.
  • That it can lead to problems with dependency.

What researchers have found

In 2012, British researchers published a review of 5 studies that had looked at Tramadol to treat premature ejaculation. Interestingly, they also attempted to explain how it actually works.

They say that although it’s still not totally clear, there are two possible actions that occur. They explain that it works as a weak μ-opioid receptor agonist. But then go on to say that the more likely explanation is that it inhibits neuronal re-uptake of serotonin and norepinephrine.

Effects of Tramadol on lasting time

In their review of the 5 studies published between 2006 and 2012, this is a brief summary of what they found:

Study 1

After 8 weeks of 50 mg Tramadol, the average lasting time of guys went from just 19 seconds to 243. That’s 13 times longer.

Study 2

After 8 weeks on 25 mg Tramadol, the average time increased from 70.2 to 442.2 seconds. So this was 6.3 times longer.

Study 3

This study actually compared Tramadol with paroxetine. They found that the paroxetine group were lasting longer, and that the Tramadol group had less rigid erections.

Study 4

They tested out both a dose of 62 mg and 89 mg, finding a respective increase of 2.4 and 2.5 times.

Study 5

They found that with a dose of 25 mg, there was an increase in lasting time from 38.83 to 154.67 – 4 times longer.

The other findings of note are that in all the studies guys reported a significant increase in their sexual satisfaction. And also their partners said they were more satisfied. You would imagine as such, but that does show that guys were happy with that kind of increase in time.

Side effects

Across those 5 studies they say that the Tramadol was well tolerated, and that the side effects experienced were only mild. Although in my view when one study says that 28.1% reported nausea, I wonder what the meaning of ‘well tolerated’ actually is!

These are the main side effects that guys reported:

  • nausea
  • somnolence
  • erectile dysfunction
  • vertigo
  • dyspepsia
  • headache
  • vomiting
  • dizziness

Potential problems with using Tramadol

It’s a standard thing in research journals to find at the end a kind of disclaimer where they have to talk about all the things that were potentially wrong with their own study.

So even though they conclude that Tramadol appears to be an effective treatment, they also describe these potential problems:

  • They only know how well it works, and how safe it is, up to 18 weeks. So the long-term effectiveness and safety of using Tramadol is still not known.
  • They don’t really know how well it compares to other drugs, like SSRI anti-depressants. Except the paroxetine study which suggests paroxetine did better.
  • That there are serious concerns about the potential for Tramadol abuse and dependence.

Tramadol dependency

So now we know that Tramadol can help many guys with premature ejaculation. The major concern though doesn’t seem to be side effects, but becoming dependent. This study isn’t the only one to mention it – this article for example also suggests that it’s a concern.

So just how bad is the risk of guys abusing or becoming addicted to Tramadol? Well, it’s not as bad as you might think, according to a 2012 research study in Egypt.

They quote another piece of research from 1999 as saying that in the United States the rate of addiction is 1 in 100,000. Something the review article also mentions, though they also say that’s a significant number.

It appears from looking at other sources also, the risk is mainly with people who have a history of drug abuse. Maybe that explains why although I personally found a craving for the Tramadol developing, I was able to stop taking it without too much trouble once I decided to.


It appears then that Tramadol could be an efficient way of helping guys deal with premature ejaculation. But as with all other medical treatments, it’s only a temporary solution and can cause other problems.

You do run the risk of having side effects – it’s an opioid after all, and so a strong drug. And there’s still much research needed into the long-term effectiveness and whether it’s better than other treatments.

There’s also the risk of addiction, dependency, abuse or whatever you want to call it. And although researchers say the risk is minimal, it could still happen to you. And if you have a history of drug use or addiction – I would try something else instead.

Your views

Have you tried Tramadol to help you last longer? Did it work, and did you have any side effects? Let me know in the comments below.

296 CommentsLeave a comment

    • Hi Chims
      Hopefully it will stay that way. If you do start to get side effects, keep an eye on how you feel though.

  • Please Ethan I just want to know of taking tramadol could cause low sperm count and is there proof that shows it can cause infertility in men for those that don’t have a child before

    Please kindly help

    • Hi Dammy
      I’ve seen a research study about reduced sperm quality in rats with heavy tramadol use. But there are no studies done about the effect on humans, and I don’t know of any showing it can cause infertility.

  • I had a severe headache on the top right coner of my head, always felt dizzy and continuous vomiting for about two days on the first occasion. But on the other two occasions, surprisingly I found out that the drink “Teem” actually helped me suppress the vomiting. But every other side effects were consistent.

    • Hi Joseph
      I’d say that’s a clear sign not to take Tramadol. Even if you can find something that helps those symptoms, it’s not good to have them in the first place.

  • Thank for the helpful article. I had a similar experience with tramadol when recovering from surgery on my foot. I wasn’t expecting the sex boost, but it was very welcome. I just wish it didn’t have side effects etc otherwise I’d be taking this stuff every day! T

    • Hi T
      You’re welcome. Yeah, it’s funny when you discover the effect yourself! But it’s a big shame it’s not so ideal to take on an ongoing basis.

  • guys thanks for ur comments, I really I appreciate that but to my own understanding tramadol” shouldn’t be use as students and youth like us. it’s only can be used by elderly people that have come up of Age. so youth like us have natural strength that God have giving to us, so lets forget about this so called drug.

    • Hi Angus
      I’m not sure why you think tramadol is only used by elderly people – doctor’s prescribe it to people of all ages if they are in pain, which is its main purpose. But I do agree that if you can find some natural strength, it’s preferable to taking strong medication!

    • Hi Valentine
      Yes, I’d stop using it. If it doesn’t get better after a week, maybe mention it to your doctor to see what they say.

  • Dear Ethan,
    I found the same accidentaly, few days before my marriage, nd it was like a gift. Although, i was familiar with Tramadol addiction and its insomaniac side effect, but i didnt know, it prolongs ur sexual intercourse time. I have searched a number of studies. Your site is the most conclusive and simple.
    I have a question for you, but you may not be able to reply as u r not a doctor, but i have to ask. I have sex twice in a week, as i m away from home for work. before having sex, i take 37.5 mg tramadol, and after an hour, it becomes like heaven, its not just sex, but its everything. But the remaining week, i dont take them.
    Do you think, this comes under addiction, and is it enough to cause problems.
    If it can cause problems, what could they be. My sleep has been affected slightly, although its been a year that i m taking them nd i cud sleep very well. Its been recent day that i can’t sleep early. 2nd, has it been known for tramadol to cause impotency for long term use,, if yes, whether this amount that i take, could cause this.
    3rd, Does it causes some permanent weakness in intensity of your erection, as sometimes, it does cauases lesser intense erection, please respond, i shall be very grateful

    • Hi Zooshoo
      You’re right in that I’m not a doctor, so any advice I give is just my opinion, based on my own experience and research I’ve done like you have. The feeling of heaven is a well known effect of tramadol. That doesn’t mean you’re addicted yet, but that feeling is something that people do become addicted to, if that makes sense? In terms of what the problems could be with addiction, well it’s best to look online for tramadol addiction and you’ll find medical articles with better information than I can offer in a brief comment.
      I don’t know about tramadol causing impotency in long-term use. I just don’t think enough studies have been done to conclude anything. In terms of erection weakness, again I’m not sure, but I do know some guys say that it can affect their erection strength.
      Sorry I can’t offer more conclusive responses to your questions. I would, however, say that a year is a long time to be using such a strong drug. I would personally be questioning whether it’s a good thing or not. I think perhaps talking it over with your doctor would be a helpful step to take.

      • Thanx a lot for your quick Response Ethan.

        Where I come from, its hard to find doctors with such specialities. Although, One doctor mentioned that, using tramadol twice a week, 37.5 mg, will not cause any side effects, and shows my control our its use, as I dont feel the need to use it for the rest of the week.
        Do you know, any other, drugs, with minimal side effects, and better result, if yes please name them,, as after all, tramadol wasnt made for this purpose.
        I will add one thing more, that its not for PE, but people with normal erection, can use it too, as the it increases the pleasure too.

        • You’re welcome! I undersatand – not everyone has easy access to the kind of medical help they’d like to have. I guess the question then, is how sure are you that you can maintain that controlled usage?
          I don’t know of any other drug which is as effective as tramadol, other than anti-depressants which need to be prescribed, and I’m personally not in favor of taking. My preferred solution is to use desensitizing sprays, condoms and natural techniques in the long run.

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